Lipitor Pills are HMG CoA reductase inhibitors (an enzyme which takes part in the synthesis of sterols including cholesterol). It contains the active ingredient Atorvastatin.
The mechanism of the action of Lipitor is simple. It inhibits a cholesterol synthesis in liver, and also enhances the level of receptors of lipoproteins of the low density on the surface of the hepatic cells, so that a cholesterol catabolism is increased.
In people with increased cholesterol level, Lipitor pills lower the risk of atherosclerosis, and also other cardiovascular diseases. It enhances the vascular lumen and improves the blood circulation.
In a couple of months of taking Lipitor, the average reduction of level of the general cholesterol happens by 30-40%, and lipoproteins of the low density are reduced by 40-60%. The therapeutic effect develops gradually, and therefore, the medicine is taken for a long time in order to achieve the maximal result.
Directions for the use of Lipitor Pills
Lipitor is prescribed in combination with diet to lower the cholesterol level and LDL in patients with primary hypercholesteremia.
The medicine is also used for the prevention of the cardiovascular diseases in patients with increased cholesterol level in the blood.
Contraindications for the use
- Liver failure
- Increased activity of liver enzymes of the unknown origin
- The active phase of hepatitis
- Individual tolerability of atorvastatin
- Age of under 18 years
Usage and doses of Lipitor Pills
The dose of Lipitor Pills is prescribed according to the medical image of a patient: age, initial cholesterol level in the blood, and relevant cardiovascular diseases, and a general condition of the internals.
- Lipitor is used once per day regardless of the meals
- The initial dose of Lipitor is 10 mg per day
- Gradually, depending on the therapeutic effect, the dose is increased up to 40-80 mg per day
- Senior patients are not needed to lower the daily dose
- If liver diseases, Lipitor should be used in the minimal doses, not more than 20-30 mg per day
On the average, the therapeutic effect develops gradually and gains its maximum in 6-8 weeks. Then, the maintaining therapy is required within 3-12 months, depending on the patient’s health.
The use of Lipitor pills is pointless without diet. To effectively lover the cholesterol level, it is necessary to reduce the consumption of food rich in the vegetable and animal fats.
Side effects of Lipitor Pills
Data about the side effects is numerically insignificant. In most cases, the medical therapy with Lipitor goes without severe side effects. In some cases, there are transient symptoms such as headache, dizziness, unpleasant dreams, rapid heartbeat, and nausea.
Using the medicine in doses more than 80 mg per day, a liver dysfunction is probable, and therefore the dosage regimen should be followed.
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